Switch-Like Roles for Polycomb Proteins from Neurodevelopment to Neurodegeneration

Polycomb Group (PcG) proteins are best-known for maintaining repressive or active chromatin states that are passed on across multiple cell divisions, and thus sustain long-term memory of gene expression. PcG proteins engage different, partly gene- and/or stage-specific, mechanisms to mediate spatiot...

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Bibliographic Details
Main Authors: Anke Hoffmann, Vincenza Sportelli, Michael Ziller, Dietmar Spengler
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Epigenomes
Subjects:
Online Access:https://www.mdpi.com/2075-4655/1/3/21