Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment

Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment

The role of NLRP12 in immunity to bacterial infection is controversial as varied and contrasting results have been published using C57BL/6 mice. Here the authors shed light on this issue, showing that unlike C57BL/6N mice, C57BL/6J mice have a missense point mutation in NLRP12 that is associated wit...

Full description

Bibliographic Details
Main Authors: Tyler K. Ulland, Nidhi Jain, Emma E. Hornick, Eric I. Elliott, Gwendolyn M. Clay, Jeffrey J. Sadler, Kathleen A. M. Mills, Ann M. Janowski, A. Paige Davis Volk, Kai Wang, Kevin L. Legge, Lokesh Gakhar, Mohammed Bourdi, Polly J. Ferguson, Mary E. Wilson, Suzanne L. Cassel, Fayyaz S. Sutterwala
Format: Article
Language:English
Published: Nature Publishing Group 2016-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13180

Internet

https://doi.org/10.1038/ncomms13180

Similar Items