Extracellular vesicles released from hiPSC-derived MSCs attenuate chronic prostatitis/chronic pelvic pain syndrome in rats by immunoregulation

Abstract Background Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is an intractable nonbacterial inflammatory disease. Mesenchymal stem cells (MSCs) derived from human induced pluripotent stem cells (hiPSCs, iMSCs) have been well documented for the management of inflammatory and autoimm...

Full description

Bibliographic Details
Main Authors: Xufeng Peng, Hailin Guo, Ji Yuan, Yu Chen, Yuguo Xia, Lin Wang, Ying Wang, Yichen Huang, Hua Xie, Yang Wang, Fang Chen
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-021-02269-x