Antigen-Specific Immunoadsorption With the Glycosorb® ABO Immunoadsorption System as a Novel Treatment Modality in Pure Red Cell Aplasia Following Major and Bidirectional ABO-Incompatible Allogeneic Hematopoietic Stem Cell Transplantation

Pure red cell aplasia (PRCA) after ABO-incompatible allogeneic hematopoietic stem cell transplantation (HSCT) is caused by persisting host-derived isohemagglutinins directed against donor red blood cell (RBC) antigens. ABO antigen-specific immunoadsorption (ABO-IA) with Glycosorb®, commonly used for...

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Main Authors: Ammon Handisurya, Nina Worel, Werner Rabitsch, Marija Bojic, Sahra Pajenda, Roman Reindl-Schwaighofer, Wolfgang Winnicki, Andreas Vychytil, Hanna A. Knaus, Rainer Oberbauer, Kurt Derfler, Philipp Wohlfarth
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.585628/full