Inter-relationship between microsatellite instability, thymidylate synthase expression, and p53 status in colorectal cancer: implications for chemoresistance

<p>Abstract</p> <p>Background</p> <p>Studies indicate that thymidylate synthase (TS) expression, p53 and mismatch repair status have potential to influence colorectal cancer (CRC) outcome. There is, however, little data on the inter-relationship between these three mark...

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Bibliographic Details
Main Authors: Wort Richard, Popat Sanjay, Houlston Richard S
Format: Article
Language:English
Published: BMC 2006-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/150