Phenotypic Resemblance to Neuropsychiatric Disorder and Altered mRNA Profiles in Cortex and Hippocampus Underlying IL15Rα Knockout

Phenotypic Resemblance to Neuropsychiatric Disorder and Altered mRNA Profiles in Cortex and Hippocampus Underlying IL15Rα Knockout

BackgroundPrevious studies of the functions of IL15Rα have been limited to immune activities and skeletal muscle development. Immunological factors have been identified as one of the multiple causes of psychosis, and neurological symptoms have been described in IL15Rα knockout (KO) mice. Seeking to...

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Bibliographic Details
Main Authors: Yi He, Yuxin Yu, Yanan Li, Weicheng Duan, Zuoli Sun, Jian Yang, Abba J. Kastin, Weihong Pan, Yan Zhang, Kang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Neuroscience
Subjects:
IL15Rα
RNA-seq
gene set enrichment analysis
neuroscience
overlap analysis
lipid metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2020.582279/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2020.582279/full

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