The SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the ongoing coronavirus disease 2019 pandemic. How SARS-CoV-2 regulates cellular responses to escape clearance by host cells is unknown. Autophagy is an intracellular lysosomal degradation pathway for the clearance of v...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-05-01
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Series: | Cell Discovery |
Online Access: | https://doi.org/10.1038/s41421-021-00268-z |