The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock
The circadian clock regulates rhythms of physiology and metabolism in response to environmental cues such as food intake. Here, the authors show that tight junction protein 1 (TJP1) interacts with period 1 and modulates its nuclear translocation in a mTOR-dependent manner.
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-14470-2 |