Excessive Iron Availability Caused by Disorders of Interleukin-10 and Interleukin-22 Contributes to High Altitude Polycythemia

Excessive Iron Availability Caused by Disorders of Interleukin-10 and Interleukin-22 Contributes to High Altitude Polycythemia

Background: Because the pathogenesis of high altitude polycythemia (HAPC) is unclear, the aim of the present study was to explore whether abnormal iron metabolism is involved in the pathogenesis of HAPC and the possible cause.Methods: We examined the serum levels of iron, total iron binding capacity...

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Bibliographic Details
Main Authors: Yun-Sheng Liu, He Huang, Si-Min Zhou, Huai-jun Tian, Peng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Physiology
Subjects:
erythrocytosis
high altitude
cytokine
iron metabolism
hepcidin
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00548/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.00548/full

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