Evolutionary histories of expanded peptidase families in Schistosoma mansoni

Evolutionary histories of expanded peptidase families in Schistosoma mansoni

Schistosoma mansoni is one of the three main causative agents of human schistosomiasis, a major health problem with a vast socio-economic impact. Recent advances in the proteomic analysis of schistosomes have revealed that peptidases are the main virulence factors involved in the pathogenesis of thi...

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Bibliographic Details
Main Authors: Larissa Lopes Silva, Marina Marcet-Houben, Adhemar Zerlotini, Toni Gabaldón, Guilherme Oliveira, Laila Alves Nahum
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2011-11-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
phylogenomics
maximum likelihood analysis
homology prediction
functional annotation
proteases
paralogous families
parasite genomics
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000700013&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000700013&lng=en&tlng=en

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