Rapid countermeasure discovery against Francisella tularensis based on a metabolic network reconstruction.

Rapid countermeasure discovery against Francisella tularensis based on a metabolic network reconstruction.

In the future, we may be faced with the need to provide treatment for an emergent biological threat against which existing vaccines and drugs have limited efficacy or availability. To prepare for this eventuality, our objective was to use a metabolic network-based approach to rapidly identify potent...

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Bibliographic Details
Main Authors: Sidhartha Chaudhury, Mohamed Diwan M Abdulhameed, Narender Singh, Gregory J Tawa, Patrik M D'haeseleer, Adam T Zemla, Ali Navid, Carol E Zhou, Matthew C Franklin, Jonah Cheung, Michael J Rudolph, James Love, John F Graf, David A Rozak, Jennifer L Dankmeyer, Kei Amemiya, Simon Daefler, Anders Wallqvist
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3660459?pdf=render

Internet

http://europepmc.org/articles/PMC3660459?pdf=render

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