Physical interaction of tropomyosin 3 and STIM1 regulates vascular smooth muscle contractility and contributes to hypertension

Scope: Tropomyosin (TPM), an actin-binding protein widely expressed across different cell types, is primarily involved in cellular contractile processes. We investigated whether TPM3 physically and functionally interacts with stromal interaction molecule 1 (STIM1) to contribute to vascular smooth mu...

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Bibliographic Details
Main Authors: Fangfang Xu, Jinhang Zhu, Ye Chen, Ke He, Jizheng Guo, Suwen Bai, Ren Zhao, Juan Du, Bing Shen
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220313196