Differential effects of collagen prolyl 3-hydroxylation on skeletal tissues.

Differential effects of collagen prolyl 3-hydroxylation on skeletal tissues.

Mutations in the genes encoding cartilage associated protein (CRTAP) and prolyl 3-hydroxylase 1 (P3H1 encoded by LEPRE1) were the first identified causes of recessive Osteogenesis Imperfecta (OI). These proteins, together with cyclophilin B (encoded by PPIB), form a complex that 3-hydroxylates a sin...

Full description

Bibliographic Details
Main Authors: Erica P Homan, Caressa Lietman, Ingo Grafe, Jennifer Lennington, Roy Morello, Dobrawa Napierala, Ming-Ming Jiang, Elda M Munivez, Brian Dawson, Terry K Bertin, Yuqing Chen, Rhonald Lua, Olivier Lichtarge, John Hicks, Mary Ann Weis, David Eyre, Brendan H L Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3900401?pdf=render

Internet

http://europepmc.org/articles/PMC3900401?pdf=render

Similar Items