5-azacytidine reactivates pluripotency gene expression, affects TET2 and histone transcription and modifies chromatin organization and morphology of mammal skin fibroblasts
Phenotype expression is controlled by epigenetic regulations that guide cells through differentiation. The process is reversible and cells can be driven back to a higher plasticity state with the use of epigenetic modifiers. In this work we exposed skin fibroblasts to the demethylating agent 5-azacy...
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| Format: | Article |
| Language: | English |
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Università degli Studi di Milano
2016-06-01
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| Series: | International Journal of Health, Animal Science and Food Safety |
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| Online Access: | http://riviste.unimi.it/index.php/haf/article/view/7033 |