A Clinical Drug Library Screen Identifies Tosufloxacin as Being Highly Active against Staphylococcus aureus Persisters

To identify effective compounds that are active against Staphylococcus aureus (S. aureus) persisters, we screened a clinical drug library consisting of 1524 compounds and identified six drug candidates that had anti-persister activity: tosufloxacin, clinafloxacin, sarafloxacin, doxycycline, thiostre...

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Bibliographic Details
Main Authors: Hongxia Niu, Peng Cui, Rebecca Yee, Wanliang Shi, Shuo Zhang, Jie Feng, David Sullivan, Wenhong Zhang, Bingdong Zhu, Ying Zhang
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Antibiotics
Subjects:
Online Access:http://www.mdpi.com/2079-6382/4/3/329