Oxygen Sensitivity of Reporter Genes: Implications for Preclinical Imaging of Tumor Hypoxia
Reporter gene techniques have been applied toward studying the physiologic phenomena associated with tumor hypoxia, a negative prognostic indicator. The purpose of this study was to assess the potential adverse effects of hypoxic conditions on the effectiveness of four commonly used reporter genes:...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi - SAGE Publishing
2007-07-01
|
Series: | Molecular Imaging |
Online Access: | https://doi.org/10.2310/7290.2007.00017 |