Influence of HLA-DRB1 and HLA-DQB1 alleles on IgG antibody response to the P. vivax MSP-1, MSP-3α and MSP-9 in individuals from Brazilian endemic area.

Influence of HLA-DRB1 and HLA-DQB1 alleles on IgG antibody response to the P. vivax MSP-1, MSP-3α and MSP-9 in individuals from Brazilian endemic area.

The antibody response generated during malaria infections is of particular interest, since the production of specific IgG antibodies is required for acquisition of clinical immunity. However, variations in antibody responses could result from genetic polymorphism of the HLA class II genes. Given the...

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Bibliographic Details
Main Authors: Josué C Lima-Junior, Rodrigo N Rodrigues-da-Silva, Dalma M Banic, Jianlin Jiang, Balwan Singh, Gustavo M Fabrício-Silva, Luís C S Porto, Esmeralda V S Meyer, Alberto Moreno, Maurício M Rodrigues, John W Barnwell, Mary R Galinski, Joseli de Oliveira-Ferreira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3359319?pdf=render

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http://europepmc.org/articles/PMC3359319?pdf=render

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