Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function

<p>Abstract</p> <p>Background</p> <p>Neurodegeneration in Alzheimer's disease is associated with increased apoptosis and parallels increased levels of amyloid beta, which can induce neuronal apoptosis. Estrogen exposure prior to neurotoxic insult of hippocampal neu...

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Bibliographic Details
Main Authors: Iwamoto Sean, Irwin Ronald W, Chen Shuhua, Nilsen Jon, Brinton Roberta
Format: Article
Language:English
Published: BMC 2006-11-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/7/74