Study on the targeted therapy of oral squamous cell carcinoma with a plasmid expressing PE38KDEL toxin under control of the SERPINB3 promoter

Study on the targeted therapy of oral squamous cell carcinoma with a plasmid expressing PE38KDEL toxin under control of the SERPINB3 promoter

Abstract Oral squamous cell carcinoma (OSCC) has a poor prognosis and a high risk of recurrence. To improve the efficacy of OSCC therapy, it is of great significance to explore gene therapy for OSCC. The use of specific genes to regulate the targeted expression of suicide genes is a hot topic in gen...

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Bibliographic Details
Main Authors: Jiang Wu, Qiong Guo, Guoliang Zhang, Liying Zhao, Yvguang Lv, Jiaqi Wang, Jiguang Liu, Wei Shi
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Cancer Medicine
Subjects:
oral squamous cell carcinoma
PE38KDEL toxin
SERPINB3 promoter
targeted therapy
Online Access:https://doi.org/10.1002/cam4.2880

Internet

https://doi.org/10.1002/cam4.2880

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