Stromal Cell-Derived Factor-1 Promotes Cell Migration, Tumor Growth of Colorectal Metastasis

Stromal Cell-Derived Factor-1 Promotes Cell Migration, Tumor Growth of Colorectal Metastasis

In a mouse model of established extrahepatic colorectal metastasis, we analyzed whether stromal cellderived factor (SDF) 1 stimulates tumor cell migration in vitro, angiogenesis, tumor growth in vivo. METHODS: Using chemotaxis chambers, CT26.WT colorectal tumor cell migration was studied under stim...

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Bibliographic Details
Main Authors: Otto Kollmar, Kathrin Rupertus, Claudia Scheuer, Bastian Junker, Bettina Tilton, Martin K. Schilling, Michael D. Menger
Format: Article
Language:English
Published: Elsevier 2007-10-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Cancer
metastasis
chemokine
SDF-1
angiogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558607800662

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http://www.sciencedirect.com/science/article/pii/S1476558607800662

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