Impact of prior Dengue immunity on Zika vaccine protection in rhesus macaques and mice.

Impact of prior Dengue immunity on Zika vaccine protection in rhesus macaques and mice.

Pre-existing immunity to flaviviruses can influence the outcome of subsequent flavivirus infections. Therefore, it is critical to determine whether baseline DENV immunity may influence subsequent ZIKV infection and the protective efficacy of ZIKV vaccines. In this study, we investigated the impact o...

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Bibliographic Details
Main Authors: Rafael A Larocca, Peter Abbink, John D Ventura, Abishek Chandrashekar, Noe Mercado, Zhenfeng Li, Erica Borducchi, Rafael A De La Barrera, Kenneth H Eckels, Kayvon Modjarrad, Michael P Busch, Nelson L Michael, Dan H Barouch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009673

Internet

https://doi.org/10.1371/journal.ppat.1009673

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