Construction of an immunotoxin by linking a monoclonal antibody against the human epidermal growth factor receptor and a hemolytic toxin

Hybrid molecules obtained through conjugation of monoclonal antibodies and toxins constitute an approach under exploration to generate potential agents for the treatment of cancer and other diseases. A frequently employed toxic component in the construction of such immunotoxins is ricin, a plant tox...

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Bibliographic Details
Main Authors: ANA D AVILA, CARLOS F CALDERÓN, RITA M PEREZ, CARMEN PONS, CELIA M PEREDA, ANA R ORTIZ
Format: Article
Language:English
Published: BMC 2007-01-01
Series:Biological Research
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000200008