Global regulation of nucleotide biosynthetic genes by c-Myc.

The c-Myc transcription factor is a master regulator and integrates cell proliferation, cell growth and metabolism through activating thousands of target genes. Our identification of direct c-Myc target genes by chromatin immunoprecipitation (ChIP) coupled with pair-end ditag sequencing analysis (Ch...

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Bibliographic Details
Main Authors: Yen-Chun Liu, Feng Li, Jesse Handler, Cheng Ran Lisa Huang, Yan Xiang, Nicola Neretti, John M Sedivy, Karen I Zeller, Chi V Dang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2444028?pdf=render