Global regulation of nucleotide biosynthetic genes by c-Myc.
The c-Myc transcription factor is a master regulator and integrates cell proliferation, cell growth and metabolism through activating thousands of target genes. Our identification of direct c-Myc target genes by chromatin immunoprecipitation (ChIP) coupled with pair-end ditag sequencing analysis (Ch...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-07-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2444028?pdf=render |