The role of 6-phosphofructo-2-kinase (PFK-2)/fructose 2,6-bisphosphatase (FBPase-2) in metabolic reprogramming of cancer cells

The high rate of glucose breakdown is the fingerprint of cancer. Increased glycolysis allows tumour cells to fulfil their high energetic and biosynthetic demands. Interestingly, however, rather than metabolizing glucose in the oxidative phosphorylation pathway, cancer cells generally use glucose for...

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Bibliographic Details
Main Authors: Kinga A. Kocemba, Joanna Dulińska-Litewka, Karolina L. Wojdyła, Przemysław A. Pękala
Format: Article
Language:English
Published: Index Copernicus International S.A. 2016-09-01
Series:Postępy Higieny i Medycyny Doświadczalnej
Subjects:
Online Access:http://phmd.pl/gicid/01.3001.0009.6872