Calcium State-Dependent Regulation of Epithelial Cell Quiescence by Stanniocalcin 1a

The molecular mechanisms regulating cell quiescence-proliferation balance are not well defined. Using a zebrafish model, we report that Stc1a, a secreted glycoprotein, plays a key role in regulating the quiescence-proliferation balance of Ca2+ transporting epithelial cells (ionocytes). Zebrafish stc...

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Bibliographic Details
Main Authors: Shuang Li, Chengdong Liu, Allison Goldstein, Yi Xin, Caihuan Ke, Cunming Duan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Akt
Tor
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.662915/full