ABCA7 Regulates Brain Fatty Acid Metabolism During LPS-Induced Acute Inflammation

ABCA7 Regulates Brain Fatty Acid Metabolism During LPS-Induced Acute Inflammation

The ATP binding cassette subfamily A member 7 (ABCA7) gene is one of the significant susceptibility loci for Alzheimer’s disease (AD). Furthermore, ABCA7 loss of function variants resulting from premature termination codon in the gene are associated with increased risk for AD. ABCA7 belongs to the A...

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Bibliographic Details
Main Authors: Tomonori Aikawa, Yingxue Ren, Marie-Louise Holm, Yan W. Asmann, Amer Alam, Michael L. Fitzgerald, Guojun Bu, Takahisa Kanekiyo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer’s disease
fatty acids
inflammation
lipopolysaccharide
metabolomics
ABCA7
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.647974/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.647974/full

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