Reduced brain somatostatin in mood disorders: a common pathophysiological substrate and drug target?

Our knowledge of the pathophysiology of affect dysregulation has progressively increased, but the pharmacological treatments remain inadequate. Here, we summarize the current literature on deficits in somatostatin, an inhibitory modulatory neuropeptide, in major depression and other neurological dis...

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Bibliographic Details
Main Authors: Li-Chun eLin, Etienne eSibille
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Pharmacology
Subjects:
som
Sst
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00110/full