Proteomics Analysis to Assess the Role of Mitochondria in BRCA1-Mediated Breast Tumorigenesis

Proteomics Analysis to Assess the Role of Mitochondria in BRCA1-Mediated Breast Tumorigenesis

Mitochondria are the organelles deputed to energy production, but they are also involved in carcinogenesis, cancer progression, and metastasis, playing a role in altered energy metabolism in cancer cells. Mitochondrial metabolism is connected with several mitochondrial pathways such as ROS signaling...

Full description

Bibliographic Details
Main Authors: Antonio Concolino, Erika Olivo, Laura Tammè, Claudia Vincenza Fiumara, Maria Teresa De Angelis, Barbara Quaresima, Valter Agosti, Francesco Saverio Costanzo, Giovanni Cuda, Domenica Scumaci
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Proteomes
Subjects:
mitochondria
HIF-1α
2D-DIGE
breast cancer
BRCA1
Online Access:http://www.mdpi.com/2227-7382/6/2/16

Internet

http://www.mdpi.com/2227-7382/6/2/16

Similar Items