Retinal Ganglion Cell Loss and Microglial Activation in a SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis

Retinal Ganglion Cell Loss and Microglial Activation in a SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis

The neurodegenerative disease amyotrophic lateral sclerosis (ALS) affects the spinal cord, brain stem, and cerebral cortex. In this pathology, both neurons and glial cells are affected. However, few studies have analyzed retinal microglia in ALS models. In this study, we quantified the signs of micr...

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Bibliographic Details
Main Authors: Pilar Rojas, Ana I. Ramírez, Manuel Cadena, José A. Fernández-Albarral, Elena Salobrar-García, Inés López-Cuenca, Irene Santos-García, Eva de Lago, José L. Urcelay-Segura, José M. Ramírez, Rosa de Hoz, Juan J. Salazar
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
microglia
retina
SOD1G93A mouse model
ALS
retinal whole-mount
microglial activation
Online Access:https://www.mdpi.com/1422-0067/22/4/1663

Internet

https://www.mdpi.com/1422-0067/22/4/1663

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