Expression of PPARα modifies fatty acid effects on insulin secretion in uncoupling protein-2 knockout mice

<p>Abstract</p> <p>Aims/hypothesis</p> <p>In uncoupling protein-2 (UCP2) knockout (KO) mice, protection of beta cells from fatty acid exposure is dependent upon transcriptional events mediated by peroxisome proliferator-activated receptor-α (PPARα).</p> <p>M...

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Bibliographic Details
Main Authors: Chan Catherine B, Fatehi-Hassanabad Zahra
Format: Article
Language:English
Published: BMC 2007-03-01
Series:Nutrition & Metabolism
Online Access:http://www.nutritionandmetabolism.com/content/4/1/6