Expression of PPARα modifies fatty acid effects on insulin secretion in uncoupling protein-2 knockout mice
<p>Abstract</p> <p>Aims/hypothesis</p> <p>In uncoupling protein-2 (UCP2) knockout (KO) mice, protection of beta cells from fatty acid exposure is dependent upon transcriptional events mediated by peroxisome proliferator-activated receptor-α (PPARα).</p> <p>M...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2007-03-01
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Series: | Nutrition & Metabolism |
Online Access: | http://www.nutritionandmetabolism.com/content/4/1/6 |