Oxymatrine Inhibits Influenza A Virus Replication and Inflammation via TLR4, p38 MAPK and NF-κB Pathways

Oxymatrine (OMT) is a strong immunosuppressive agent that has been used in the clinic for many years. In the present study, by using plaque inhibition, luciferase reporter plasmids, qRT-PCR, western blotting, and ELISA assays, we have investigated the effect and mechanism of OMT on influenza A virus...

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Bibliographic Details
Main Authors: Jian-Ping Dai, Qian-Wen Wang, Yun Su, Li-Ming Gu, Hui-Xiong Deng, Xiao-Xuan Chen, Wei-Zhong Li, Kang-Sheng Li
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:International Journal of Molecular Sciences
Subjects:
TLR
Online Access:http://www.mdpi.com/1422-0067/19/4/965