Assessment of molecular differentiation in FFPE colon adenocarcinoma tissues using PCA analysis of MALDI IMS spectral data

Assessment of molecular differentiation in FFPE colon adenocarcinoma tissues using PCA analysis of MALDI IMS spectral data

MALDI IMS datasets comprise huge amounts of spectra and their interpretation requires the use of multivariate statistical methods. MALDI IMS spectral data have been processed using sequential principal component analysis and 2-D peak distribution tests so as to investigate the molecular differentiat...

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Bibliographic Details
Main Authors: Irene Panderi, Kimberly Perez, Lulu Cao, Lelia Noble, Kara Lombardo, Thomas J. Walsh, Dionysios Pantazatos
Format: Article
Language:English
Published: Betasciencepress Publishers 2017-06-01
Series:Journal of Applied Bioanalysis
Subjects:
MALDI-TOF IMS
imaging mass spectrometry
colorectal adenocarcinoma
formalin-fixed paraffin-embedded tissues
principal component analysis.
Online Access:https://doi.org/10.17145/jab.17.012

Internet

https://doi.org/10.17145/jab.17.012

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