Unraveling Sugar Binding Modes to DC-SIGN by Employing Fluorinated Carbohydrates

Unraveling Sugar Binding Modes to DC-SIGN by Employing Fluorinated Carbohydrates

A fluorine nuclear magnetic resonance (<sup>19</sup>F-NMR)-based method is employed to assess the binding preferences and interaction details of a library of synthetic fluorinated monosaccharides towards dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-...

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Bibliographic Details
Main Authors: J. Daniel Martínez, Pablo Valverde, Sandra Delgado, Cecilia Romanò, Bruno Linclau, Niels C. Reichardt, Stefan Oscarson, Ana Ardá, Jesús Jiménez-Barbero, F. Javier Cañada
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
NMR
molecular recognition
lectin
glycomimetics
DC-SIGN
C-type lectins
fluorinated sugars
<sup>19</sup>F-NMR
screening
molecular dynamics
Online Access:https://www.mdpi.com/1420-3049/24/12/2337

Internet

https://www.mdpi.com/1420-3049/24/12/2337

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