Comparison of Nucleotide Sequence of P2C Region in Diabetogenic and Non-Diabetogenic Coxsackie Virus B5 Isolates

Enteroviruses are environmental triggers in the pathogenesis of type 1 diabetes mellitus (DM). A sequence of six identical amino acids (PEVKEK) is shared by the 2C protein of Coxsackie virus B and the glutamic acid decarboxylase (GAD) molecules. Between 1995 and 2002, we investigated 22 Coxsackie vi...

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Bibliographic Details
Main Authors: Cheng-Chong Chou, Kuei-Hsiang Lin, Guan-Ming Ke, Yi-Ching Tung, Jeng-Yin Cheng, Bai-Hsiun Chen
Format: Article
Language:English
Published: Wiley 2004-11-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X09702530