Highly regio- and enantioselective multiple oxy- and amino-functionalizations of alkenes by modular cascade biocatalysis
Biocatalysis can perform highly selective multi-step synthesis in one pot, but with a limited range of non-natural reactions and products. Here, the authors report regio- and enantioselective bio-cascades, able to convert styrenes into a number of nitrogen and oxygen containing chiral molecules.
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms11917 |