EZH2 regulates cofilin activity and colon cancer cell migration by targeting ITGA2 gene.

Reorganization of cytoskeleton via actin remodeling is a basic step of cell locomotion. Although cell migration of normal and cancer cells can be stimulated by a variety of intra- and extra-cellular factors, all paths ultimate on the regulation of cofilin activity. Cofilin is a small actin-binding p...

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Bibliographic Details
Main Authors: Angelo Ferraro, Themis Boni, Alexander Pintzas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4280133?pdf=render