Plasma Concentrations of Lysophosphatidic Acid and Autotaxin in Abstinent Patients with Alcohol Use Disorder and Comorbid Liver Disease

Plasma Concentrations of Lysophosphatidic Acid and Autotaxin in Abstinent Patients with Alcohol Use Disorder and Comorbid Liver Disease

Lysophosphatidic acid (LPA) is an endogenous lysophospholipid and a bioactive lipid that is synthesized by the enzyme autotaxin (ATX). The ATX–LPA axis has been associated with cognitive dysfunction and inflammatory diseases, mainly in a range of nonalcoholic liver diseases. Recently, preclinical an...

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Bibliographic Details
Main Authors: María Flores-López, Nuria García-Marchena, Francisco Javier Pavon, Estrella Lara, Oscar Porras-Perales, Pedro Araos, Nerea Requena-Ocaña, Sandra Torres-Galván, M. Carmen Mañas-Padilla, Gabriel Rubio, Juan Suárez, Luis J. Santín, Fernando Rodríguez de Fonseca, Estela Castilla-Ortega, María I. García-Fernández, Antonia Serrano
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomedicines
Subjects:
lysophosphatidic acid
autotaxin
alcohol use disorder
liver disease
comorbidity
Online Access:https://www.mdpi.com/2227-9059/9/9/1207

Internet

https://www.mdpi.com/2227-9059/9/9/1207

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