Suppression of Allogeneic Response by Viral IL-10 Gene Transfer

Th1 cell activation and cytokine production shift the balance between Th1 and Th2, favoring the upregulation of proinflammatory activity that leads to destruction of allogeneic hepatocytes following transplantation. Th2-type cytokines, such as IL-10, have immune regulatory function. The aim of this...

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Bibliographic Details
Main Authors: Kenji Fujisawa, Shinya Saito DR., Yutaka Okada, Toshiyosi Fujiwara, Takahito Yagi, Hiromi Iwagaki, Noriaki Tanaka
Format: Article
Language:English
Published: SAGE Publishing 2003-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000003108746920