The structure of an RNAi polymerase links RNA silencing and transcription.

RNA silencing refers to a group of RNA-induced gene-silencing mechanisms that developed early in the eukaryotic lineage, probably for defence against pathogens and regulation of gene expression. In plants, protozoa, fungi, and nematodes, but apparently not insects and vertebrates, it involves a cell...

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Bibliographic Details
Main Authors: Paula S Salgado, Minni R L Koivunen, Eugene V Makeyev, Dennis H Bamford, David I Stuart, Jonathan M Grimes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0040434