Adipocyte-conditioned medium induces resistance of breast cancer cells to lapatinib

Adipocyte-conditioned medium induces resistance of breast cancer cells to lapatinib

Abstract Background The existence of a cross-talk between peritumoral adipocytes and cancer cells has been increasingly investigated. Several studies have shown that these adipocytes protect tumor cells from the effect of anticancer agents. Methods To investigate a potential protective effect of adi...

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Bibliographic Details
Main Authors: A. Geneste, M. N. Duong, L. Molina, L. Conilh, S. Beaumel, A. Cleret, K. Chettab, M. Lachat, L. P. Jordheim, E. L. Matera, C. Dumontet
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Pharmacology and Toxicology
Subjects:
HER2
Breast cancer
Resistance
Adipocytes
Lapatinib
Online Access:http://link.springer.com/article/10.1186/s40360-020-00436-z

Internet

http://link.springer.com/article/10.1186/s40360-020-00436-z

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