Cell-SELEX Identifies a “Sticky” RNA Aptamer Sequence

Cell-SELEX is performed to select for cell binding aptamers. We employed an additional selection pressure by using RNAse to remove surface-binding aptamers and select for cell-internalizing aptamers. A common RNA sequence was identified from independent cell-SELEX procedures against two different pa...

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Bibliographic Details
Main Authors: Partha Ray, Rebekah R. White
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.1155/2017/4943072