Bioenhanced advanced third generation solid dispersion of tadalafil: Repurposing with improved therapy in pyelonephritis

Bioenhanced advanced third generation solid dispersion of tadalafil: Repurposing with improved therapy in pyelonephritis

Tadalafil (TDL) a BCS-II drug is recently reported for repurposing nephroprotective effect in Pyelonephritis (PN). However, poor water solubility and dissolution rate limited oral bioavailability pose serious challenges in its therapeutic applications. We present an advanced third generation Solid D...

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Bibliographic Details
Main Authors: Prashant P. Mande, Sagar S. Bachhav, Padma V. Devarajan
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Phosphodiesterase-5
Lipopolysaccharide
Kidney infection
Eudragit EPO
Kidney failure
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087617300739

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http://www.sciencedirect.com/science/article/pii/S1818087617300739

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