In vitro Toxico-genomics of Etoposide Loaded Gelatin Nanoparticles and Its in-vivo Therapeutic Potential: Pharmacokinetics, Biodistribution and Tumor Regression in Ehrlich Ascites Carcinoma (EAC) Mice Model

In vitro Toxico-genomics of Etoposide Loaded Gelatin Nanoparticles and Its in-vivo Therapeutic Potential: Pharmacokinetics, Biodistribution and Tumor Regression in Ehrlich Ascites Carcinoma (EAC) Mice Model

Globally, breast cancer is the foremost cause of mortality among women detected with cancer, with 21% diagnosed in India alone. Etoposide loaded gelatin nanoparticles (EGNP) were prepared and its physical characterization (size:150nm±0.241; zeta potential −29.32 mV) was done along with in-vitro stud...

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Bibliographic Details
Main Authors: Imran Moin, Largee Biswas, Md Zafaryab, Namrata Kumari, Ankita Leekha, Disha Mittal, Anita Kamra Verma
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Nanotechnology
Subjects:
EGNPs
biodistribution
pharmacokinetics
necroptosis
apoptosis
toxicogenomics
Online Access:https://www.frontiersin.org/articles/10.3389/fnano.2021.624083/full

Internet

https://www.frontiersin.org/articles/10.3389/fnano.2021.624083/full

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