Hyperinvasive Meningococci Induce Intra-nuclear Cleavage of the NF-κB Protein p65/RelA by Meningococcal IgA Protease.

Hyperinvasive Meningococci Induce Intra-nuclear Cleavage of the NF-κB Protein p65/RelA by Meningococcal IgA Protease.

Differential modulation of NF-κB during meningococcal infection is critical in innate immune response to meningococcal disease. Non-invasive isolates of Neisseria meningitidis provoke a sustained NF-κB activation in epithelial cells. However, the hyperinvasive isolates of the ST-11 clonal complex (S...

Full description

Bibliographic Details
Main Authors: Anissa Besbes, Salomé Le Goff, Ana Antunes, Aude Terrade, Eva Hong, Dario Giorgini, Muhamed-Kheir Taha, Ala-Eddine Deghmane
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005078

Internet

https://doi.org/10.1371/journal.ppat.1005078

Similar Items