Ambiguous allele combinations in HLA Class I and Class II sequence-based typing: when precise nucleotide sequencing leads to imprecise allele identification

<p>Abstract</p> <p>Sequence-based typing (SBT) is one of the most comprehensive methods utilized for HLA typing. However, one of the inherent problems with this typing method is the interpretation of ambiguous allele combinations which occur when two or more different allele combin...

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Bibliographic Details
Main Authors: Larsen Paula, Wang Lu, Robbins FuMeei, Chen Deborah, Barracchini Kathleen C, Adams Sharon D, Luhm Robert, Stroncek David F
Format: Article
Language:English
Published: BMC 2004-09-01
Series:Journal of Translational Medicine
Subjects:
HLA
Online Access:http://www.translational-medicine.com/content/2/1/30