Structural Model of the Extracellular Assembly of the TCR-CD3 Complex

Structural Model of the Extracellular Assembly of the TCR-CD3 Complex

Antigen recognition of peptide-major histocompatibility complexes (pMHCs) by T cells, a key step in initiating adaptive immune responses, is performed by the T cell receptor (TCR) bound to CD3 heterodimers. However, the biophysical basis of the transmission of TCR-CD3 extracellular interaction into...

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Bibliographic Details
Main Authors: Aswin Natarajan, Vidushan Nadarajah, Klara Felsovalyi, Wenjuan Wang, Vivian R. Jeyachandran, Riley A. Wasson, Timothy Cardozo, Clay Bracken, Michelle Krogsgaard
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716302169

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http://www.sciencedirect.com/science/article/pii/S2211124716302169

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