Premetazoan Origin of the Hippo Signaling Pathway

Nonaggregative multicellularity requires strict control of cell number. The Hippo signaling pathway coordinates cell proliferation and apoptosis and is a central regulator of organ size in animals. Recent studies have shown the presence of key members of the Hippo pathway in nonbilaterian animals,...

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Bibliographic Details
Main Authors: Arnau Sebé-Pedrós, Yonggang Zheng, Iñaki Ruiz-Trillo, Duojia Pan
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471100009X