Visual properties of transgenic rats harboring the channelrhodopsin-2 gene regulated by the thy-1.2 promoter.

Visual properties of transgenic rats harboring the channelrhodopsin-2 gene regulated by the thy-1.2 promoter.

Channelrhodopsin-2 (ChR2), one of the archea-type rhodopsins from green algae, is a potentially useful optogenetic tool for restoring vision in patients with photoreceptor degeneration, such as retinitis pigmentosa. If the ChR2 gene is transferred to retinal ganglion cells (RGCs), which send visual...

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Bibliographic Details
Main Authors: Hiroshi Tomita, Eriko Sugano, Yugo Fukazawa, Hitomi Isago, Yuka Sugiyama, Teru Hiroi, Toru Ishizuka, Hajime Mushiake, Megumi Kato, Masumi Hirabayashi, Ryuichi Shigemoto, Hiromu Yawo, Makoto Tamai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2772120?pdf=render

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http://europepmc.org/articles/PMC2772120?pdf=render

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