Development and characterization of novel chimeric monoclonal antibodies for broad spectrum neutralization of rabies virus.

Development and characterization of novel chimeric monoclonal antibodies for broad spectrum neutralization of rabies virus.

Current post-exposure prophylaxis for rabies virus infection has several limitations in terms of supply, cost, safety, and efficacy. Attempts to replace human or equine rabies immune globulins (HRIG or ERIG) have been made by several companies and institutes. We developed potent monoclonal antibodie...

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Bibliographic Details
Main Authors: Pan Kyeom Kim, Sun Ju Keum, Modupe O V Osinubi, Richard Franka, Ji Young Shin, Sang Tae Park, Man Su Kim, Mi Jung Park, Soo Young Lee, William Carson, Lauren Greenberg, Pengcheng Yu, Xiaoyan Tao, Wang Lihua, Qing Tang, Guodong Liang, Madhusdana Shampur, Charles E Rupprecht, Shin Jae Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5646816?pdf=render

Internet

http://europepmc.org/articles/PMC5646816?pdf=render

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