Aptameric Probe Specifically Binding Protein Heterodimer Rather Than Monomers

Abstract Dimerization of proteins occurs frequently and plays integral roles in biological processes. However, no single molecular probe is available for in situ detection of protein dimers on cells and tissues because of the difficulty of isolating complete protein dimers for probe preparation and...

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Bibliographic Details
Main Authors: Tao Bing, Luyao Shen, Junyan Wang, Linlin Wang, Xiangjun Liu, Nan Zhang, Xiao Xiao, Dihua Shangguan
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.201900143